Steve Allen's guests include Diana Dors, Mort Sahl, Jayne Meadows and regulars Louie Nye, Don Knotts, Pat Harrington Jr., Gabe Dell, Dayton Allen and Bill Dana. Everyone bids farewell on this final live show of the four year series.
This program, the last of the series, opens with Allen backstage, where he spots guests preparing for their appearances and talks with bandleader Les Brown. Following this exchange, Diana Dors sings; Allen introduces a repeat showing of the very popular sketch "Wife of Frankenstein," a horror musical starring Jayne Meadows as the bride, Louis Nye as the monstrous groom, and Allen as Dr. Frankenstein; and comedian Mort Sahl does a routine on the upcoming elections, making suggestions about which television shows might be appropriate vehicles for political guest appearances. Later, Allen introduces each of the series regulars and presents them in favorite performances, including Bill Dana as Jose Jimenez; Dayton Allen as Dudley E. Dudley; Pat Harrington as the Great John L., an ex-prizefighter turned restaurant owner; Don Knotts as a weatherman who must ad-lib his report; Gabe Dell as a former star of horror movies; and Louis Nye as Harvey Footlight, ex-Vaudeville star.
The cast then pay tribute to Allen and present a clip of him as sportscaster Bill Allen in which he falls into a laughing fit which makes it hard for him to talk. Finally, each of the regulars does a spot for Plymouth, including Louis Nye as Gordon Hathaway; and the cast gathers backstage for an end-of-series party.